The US66 cars lost control of the vehicle and had crashed into cars while traveling on the Pennsylvania highway amid a record snowstorm, killing at least two people.

55 trucks and 11 passenger cars collided, causing a 1.6 km crash on the west lane of the 80 interstate highway in Clinton County, Pennsylvania, at 15:00 on December 16, police said

By the afternoon of December 17, the road was still closed for the rescue team to relocate the vehicles.

Officials did not say whether the cause of the accident was due to the weather, but asked people to stay at home and not go to the street if not absolutely necessary.

The biggest blizzard in the past few years made landfall from North Carolina to Maine, causing congestion in many places and the cancellation of more than 1,300 flights.

Some states have declared a state of emergency, closing schools and banning large vehicles from traveling on highways.

At least five people were killed in the first US blizzard this year, including a man who was stabbed by a tractor while plowing in Pittsburgh, Pennsylvania's second largest city.